Canadian Research osteoprotegerin (OPG)

Meeting with professor Jérôme Frenette about osteoprotegerin (OPG).

We are producing a video series of interviews with Canadian researchers working on DMD. We have met many professors, and our videos will be coming up soon.  We wish to connect you, the DMD community, with the professors. You will be delighted to know their deepest motivation and devotion. They love to know your face; you are the people that will be impacted by their discovery. Also, the video is a very good medium to offer an understanding of scientific concepts which are not always so easy to grasp.


Video series coming up…

We met and interviewed professor Jérôme Frenette of the Rehabilitation Department of Laval University who is currently working on a potential treatment for Duchenne muscular dystrophy. He presented some very promising work with his team at the University Hospital Center of Quebec on osteoprotegerin (OPG).


Interesting information about OPG

• OPG is a protein well known for its protective role against osteoporosis, where its name comes from, osteoprotegerin.
• OPG reduces damage and inflammation.
• OPG eases Duchenne muscular dystrophy, especially in fast-twitch skeletal muscle.
• OPG can simultaneously treat osteoporosis and muscle degeneration in patients with DMD.
• Dystrophic muscles can be protected without correcting the dystrophin gene. The team from the Faculty of Medicine at Laval University in Quebec City has just demonstrated that this protein could be a new avenue of treatment for Duchenne muscular dystrophy (DMD).


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1 reply
  1. Genericcialisonline
    Genericcialisonline says:

    Hi. Thanks for the query.. Difficulty in swallowing is also known as Dysphagia and it can be due to causes that can be related to throat or oropharynx like: Muscular dystrophy, Parkinsonism, Zenker”s Diverticulum that is a small pouch formed just above foodpipe. etc. While it can also be due to problems with the oesophagus or food pipe like acid reflux, esophageal stricture, tumor, esophagitis, Scleroderma etc.. So first of all you should get a Barium x ray and Endoscopy done to rule out the problem. In case if an ENT is not available then a Gastroenterologist or a Medicine specialist can also be consulted and appropriate management can be done.. Although cancer is not always the cause but early investigation is a must to diagnose and treat the problem.. Hope this helps.. Regards.


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